Our Products
The initial focus of CBDI will be on bioreactor development for the construction of tissues for blood vessel replacement/bypass and creation of functional and cosmetic skeletal muscle tissue. CBDI's first product was a second-generation bioreactor for skin-stretching, developed for use by WFIRM in clinical trials for a Department of Defense contract.
Please contact us for more information and to determine if we can meet your requirements either through a standard product or custom development.
Advantages
CBDI through it's association with the Wake Forest University Institute of Regenerative Medicine is at the leading edge of bioreactor design. Technology is being developed in the areas of automatic control, monitoring of tissue growth, and automatic data gathering. CBDI bioreactors are also being used in a wide range of experimental applications enabling modular designs with broad applicability to be developed. You can be sure that the technology available from CBDI will always be state of the art and at the cutting edge of regenerative medicine.
Our Goals
The long term goal is to produce CBDI bioreactors that can be used not only in the research laboratory, but also for GLP and GMP studies: Providing the full "bench to bedside" approach to bioreactor technology development. CBDI bioreactors are computer controlled using a flexible and configurable interface to LabView.
Results
An engineered blood vessel pulses in action
The application of appropriate biomechanical forces to ensure rapid tissue formation and function is a cornerstone of the technologies and instrumentation being developed by CBDI.
A lab-grown, human heart valve functions in rhythm
Decellularized and seeded with the patient's cells, a heart valve matrix is placed in a CBDI bioreactor to mimic in vivo growing conditions. Through this process, the structural integrity and native functionality is achieved.
Engineered skeletal muscle being stretched in the lab
A computer-controlled system subjects the muscle/collagen strands to cyclical stretching, a preconditioning that forces the cells to align and the muscle bundles to fuse, allowing CBDI's bioreactors to create functional muscle tissue.
