About Regenerative Medicine
Engineered tissue
Cell growth at the microscopic level
An engineered heart valve
Regenerative medicine, the repair and replacement of damaged cells, organs, and tissues, is emerging as a exciting new therapeutic tool in the scientific community. This new field is refining approaches to repair damaged tissue in vivo; and to grow tissues and organs in vitro to implant them in the body. Notably important is the fact that when growing tissues and organs from cells harvested from the patient, the effects of tissue and organ rejection and inflammation are substantially eliminated.
Tissue engineering and regenerative medicine encompass the repair and replacement of damaged cells, tissues and organs, and as such, have the potential to revolutionize the treatment of human disease. The efficient and widespread application and expansion of tissue engineering and regenerative medicine will be critically dependent on parallel development of enabling technologies such as bioreactors. Bioreactors are necessary for the growth and maturation of human tissues in the laboratory, as well as for the secure shipment of these tissues and organs to the surgeon for implantation.
Regenerative medicine addresses a huge unmet medical need, and this need is reflected by the fact that the worldwide market for regenerative medicine is conservatively estimated to be $500 billion by 2010 (see 2020 A New Vision: A Future for Regenerative Medicine, available from the U.S. Department of Health and Human Services). The field is developing at a rapid rate with many clinicians and scientists in the field believe engineered tissue and organs will begin to be used within five years and widely adopted within ten years.
For the potential of regenerative medicine to be fully realized, manufacturing equipment and techniques to grow tissues and organs must be developed and delivered to the marketplace. This equipment and related know how are collectively known as a bioreactor. The development of bioreactor products requires a unique blend of basic medical research, engineering and manufacturing capabilities that Creative Bioreactor Designs, Inc. is uniquely positioned to deliver. Read More about our Technology.
Regenerative Medicine and Bioreactors
The Bioreactor is laboratory device that mimics/recreates important features and characteristics that the organ or tissue of interest would be exposed to in the body.
In essence, the bioreactor is used to mature or develop a tissue outside the human body, for subsequent implantation.
In regenerative medicine, Bioreactors are one of the primary enabling technologies.
Additional Reading
National Institutes of Health. Regenerative Medicine Fact Sheet (pdf - 101kb)
2020: A New Vision - A Future for Regenerative Medicine(web page)
Multi-Agency Tissue Engineering Science (MATES) (web page)
Great Expectations: Private Sector Activity in Tissue Engineering... (pdf - 342kb) (purchase)